Sentrin-Specific Protease 7 Recombinant Protein 91-151 from ProSci, Inc

Description

Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1

Product Specs
ItemSentrin-Specific Protease 7 Recombinant Protein
CompanyProSci, Inc
Price Pricing Info Supplier Page View Company Product Page
Catalog Number91-151
Quantity0.05 mg
PurityGreater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test
TypeRecombinant Proteins
Molecular Weight27.3 kD
SpeciesHuman
Molecule NameSENP7
Source/Expression SystemE. coli
NCBI Full Gene NameSUMO specific peptidase 7
FormatLiquid
Research AreaCancer,Cell Cycle

Specifications/Features

Format: Supplied as a 0.2 um filtered solution of 20mM HEPES, 5% Glycerol, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.